Isoniazid is an antituberculous drug. It can cause peripheral neuropathy and rarely convulsions by decreasing the availability of pyridoxine (vitamin B6). Isoniazid binds to pyridoxal-5-phosphate, the active form
Amoxycillin is an extended spectrum aminopenicillin. But it is not active against penicillinase producing organism. Clavulanic acid is a penicillinase inhibitor which initially reversibly and then irreversibly inhibits
Glibenclamide is an oral hypoglycemic drug belonging to the group sulphonyl ureas. It is a second generation sulphonyl urea. Other sulphonyl ureas include – glipizide, gliclazide and glimiperide.
It is an antihelminthic drug, a newer congener of mebendazole. Mechanism of action is same as that of mebendazole. It inhibits glucose uptake into the helminth’s cells and
Metronidazole is a nitro-imidazole drug which has antiprotozoal and anti-anaerobe activity. Spectrum Protozoans – Entamoeba histolytic, Giardia lamblia, Trichomonas vaginalis Bacteria – Camphylobacter jejuni, Helicobacter pylori, Fusobacterium, Bacteriodes fragilis,
Methylergometrine produces non-physiological spasmodic contraction of the uterus in moderate to high doses and the uterus does’nt fully relax between the contractions. It also causes contraction of the
Lactulose is a semi-synthetic disaccharide composed of fructose and galactose. It is not absorbed in the intestine. It is broken down into osmotically more active products by the
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