Compromise of the left ventricular filling due to bulging of the interventricular septum into the left ventricle

Can occur due to

• Physiologically during inspiration due to increased filling of the right ventricle (because of increased venous return)
• pulmonary embolism

1. Bernheim effect
2. Mechanism of physiological split in second heart sound
3. Inspiratory decrease in systolic blood pressure and pulse volume – Mechanism
4. Paediatrics – MCQ 57 – Eisenmenger syndrome