Articles Archive for September 2010
Featured, Medicine »
Components of a joint
Enthesis refers to the point where a tendon / ligament is attached to bone
The collagen fibers are calcified at this region and integrated into bone tissue
Types
Fibrous enthesis
Fibrocartilagenous enthesis
Clinical importance:
Enthesitis (inflammation of the enthesis) is the common pathology responsible for spondyloarthropathies
Image credits: Madhero88
Medicine »
Paraproteinemia refers to increased amounts of a singly type of monoclonal gammaglobulins in the blood
It indicates an underlying immunoproliferative disorder
Types:
Depending on the type of monoclonal gammaglobulins found in blood, paraproteinemias are of 3 types
Light chain disease (light chain only present)
Heavy chain disease (heavy chain only present)
Full immunoglobulins (light chain : heavy chain ratio may vary)
Alternate name – Monoclonal gammopathy
Medicine »
Cystic fibrosis is the most important condition in which chloride levels in sweat are increased
It is measured by using sweat test
There are some other conditions which produce increased sweat chloride levels
Glycogen storage disorders
Nephrogenic diabetes insipidus
G6PD deficiency
Ectodermal dysplasia
Malnutrition
Adrenal insufficiency
Hypothyroidism
Hypoparathyroidism
Medicine »
The following drugs are known to cause peripheral neuropathy as their side effect.
Anti cancer drugs
vincristine
cisplatin
Anti epileptics
Phenytoin
Cardiac drugs
Hydralazine
Amiodarone
Perhexiline
Antibiotics
Nitrofurantoin
Isoniazid
Metronidazole
Anti leprosy
Dapsone
Cholesterol lowering drugs
Lovastatin
Indapamide
Gemfibrozil
Anti alcohol
Disulfiram
Anti HIV
Zalcitabine
Ritonavir
Didanosine
Amprenavir
Stavudine
Zidovudine
Arsenic
Medicine »
Siegert’s sign refert to short and inward curved terminal phalanges seen in Down syndrome
Named after Ferdinand Siegert, a German paediatrician