PG Blazer Blaze your way towards a medical PG seat! 2012-05-22T02:16:23Z http://pgblazer.com/feed/atom WordPress pgblazer <![CDATA[Clinical features of ovarian hyperstimulation syndrome]]> http://pgblazer.com/?p=14962 2012-05-22T02:16:23Z 2012-05-22T02:16:23Z

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Ovarian hyperstimulation syndrome can be caused by intake of the following drugs:

  • Clomiphene citrate
  • FSH / LH
  • GnRH

Clinical features of ovarian hyperstimulation syndrome are:

  • Ascites
  • Pleural effusion
  • Abdominal pain and distension
  • Renal failure
  • Liver dysfunction
  • Coagulopathy
  • Cerebrovascular accident
  • Ovarian cyst torsion and haemorrhage

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pgblazer <![CDATA[Ultrasound features of congenital diaphragmatic hernia]]> http://pgblazer.com/?p=14958 2012-05-21T00:22:15Z 2012-05-21T00:22:15Z

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Ultrasound features of congenital diaphragmatic hernia are:

  • Visualisation of abdominal organs in the chest
  • Absence of normally positioned stomach
  • Mediastinal displacement
  • Small abdominal circumference
  • Polyhydramnios

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pgblazer <![CDATA[Amino acids excreted in urine in cystinuria – Mnemonic]]> http://pgblazer.com/?p=14954 2012-05-19T00:58:47Z 2012-05-19T00:58:47Z

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Mnemonic for amino acids excreted in urine in cystinuria is: COLA

C – Cystine

O – Ornithine

L – Lysine

A – Arginine

Cystinuria is and inherited disorder which is characterised by defective renal transport mechanism. Amino acid re-absorption from the tubules is impaired.

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pgblazer <![CDATA[Positive feedback systems in the body]]> http://pgblazer.com/?p=14951 2012-05-19T00:47:40Z 2012-05-19T00:47:40Z

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In the human body, most of the control systems are negative feedback systems. But there are also a few positive feedback systems. They are:

  • Shock
  • Parturition (delivery of the baby)
  • LH surge
  • Action potential
  • Coagulation pathway
  • Entry of calcium into sarcoplasmic reticulum

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pgblazer <![CDATA[Conditions causing wormian bone formation]]> http://pgblazer.com/?p=14946 2012-05-20T02:29:27Z 2012-05-16T16:17:10Z

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Conditions causing wormian bone formation are:

  • Rickets
  • Hypothyroidism
  • Hypophosphatasia
  • Cleidocranial dysostosis
  • Osteogenesis imperfecta

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pgblazer <![CDATA[Drugs with disulfiram like action]]> http://pgblazer.com/?p=14941 2012-05-13T08:11:26Z 2012-05-13T08:10:49Z

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Disulfiram causes an acute reaction following intake of alcohol and is used for treatment of alcoholism (deterrent therapy). Some drugs produce disulfiram like reactions and hence should be avoided in patients who consume alcohol. Or the patient should stop alcohol consumption.. :-)

  • Metranidazole
  • Cephalosporins
  • Chlorpropamide
  • Furazolidine
  • Griseofulvin
  • Citrated calcium carbamide

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pgblazer <![CDATA[Theophylline – Drug interactions]]> http://pgblazer.com/?p=14938 2012-05-13T07:25:31Z 2012-05-13T07:25:31Z

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Certain drugs inhibit theophylline metabolism, thus increasing blood levels and cause toxicity:

  • Ciprofloxacin
  • Cimetidine
  • Erythromycin
  • Allopurinol
  • Oral contraceptives

Some others increase theophylline metabolism, decreasing blood levels:

  • Phenobarbitone
  • Phenytoin
  • Rifampicin

Smoking and consumption of charcoal boiled meat also increase theophylline metabolism.

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pgblazer <![CDATA[Post exposure prophylaxis – Diseases]]> http://pgblazer.com/?p=14935 2012-05-13T00:52:09Z 2012-05-13T00:52:09Z

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Post exposure prophylaxis is used for the following diseases:

  • Rabies
  • Tetanus
  • Hepatitis
  • Varicella
  • Measles (to be given within 3 days of exposure)

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 8]]> http://pgblazer.com/?p=14933 2012-05-12T01:37:35Z 2012-05-12T01:37:35Z

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Which is true?
A. Occipital lobe is a part of the cerebral cortex
B. Medulla is a part of limbic system
C. Hypothalamus is a part of brainstem
D. All of the above

Correct answer : A. Occipital lobe is a part of the cerebral cortex

Brainstem consists of midbrain, pons and medulla. Limbic system consists of Hippocampus, Amygdala, Fornix, Mammillary body, Septal nuclei and the limbic lobe (Parahippocampal gyrus, Cingulate gyrus, Dentate gyrus)

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 7]]> http://pgblazer.com/?p=14927 2012-05-09T16:10:32Z 2012-05-09T16:09:01Z

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Mechanism of development of edema in nephrotic syndrome is?
A. Sodium and water retention
B. Loss of proteins
C. Hyperlipidemia
D. Increased venous pressure

Correct answer : B. Loss of proteins

(Repeat AIIMS Nov 2010)

Explanation: In nephrotic syndrome, there is loss of proteins through the glomeruli. This results in hypoalbuminemia and decreased plasma oncotic pressure. Thus fluid moves into the extravascular compartment – development of edema.

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 6]]> http://pgblazer.com/?p=14925 2012-05-09T01:38:59Z 2012-05-09T01:38:59Z

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Active partner in lesbianism is known as:
A. Bugger
B. Femme
C. Dyke
D. Catamite

Correct answer : C. Dyke

A preferentially active lesbian (who is most often a transvestite or transsexual) is known as a butch or dyke, while the usual passive agent is called a femme.
Ref: Textbook of Forensic Medicine and Toxicology : Principles and Practice, By Krishan Vij – 5/e, p322 (accessed via google books)

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 5]]> http://pgblazer.com/?p=14923 2012-05-09T01:27:54Z 2012-05-09T01:27:54Z

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More than one codon coding for same amino acid is known as?
A. Degeneracy
B. Transcription
C. Mutation
D. Frame shift mutation

(Repeat AIIMS Nov 11, Nov 06)

Correct answer : A. Degeneracy

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pgblazer <![CDATA[Indications for sympathectomy]]> http://pgblazer.com/?p=14919 2012-05-07T00:34:50Z 2012-05-07T00:34:50Z

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Indications for sympathectomy are:

  • Hyperhydrosis
  • Causalgia
  • Raynaud’s disease caused by stable arterial occlusions
  • Frost bite sequelae
  • Thromboangitis / distal arterial occlusions
  • Reflex sympathetic dystrophy
  • Inoperable atherosclerotic occlusions with pain or limited tissue loss

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pgblazer <![CDATA[Raynaud’s phenomenon Mnemonic]]> http://pgblazer.com/?p=14916 2012-05-06T15:03:22Z 2012-05-06T15:03:22Z

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Mnemonic for sequence of changes in Raynaud’s phenomenon: PCR (Polymerase Chain Reaction)

PCR Mnemonic stands for

P – Pallor (Stage of local syncope – extremity becomes pale)
C – Cyanosis (Stage of local asphyxia – extremity becomes cyanosed)
R – Redness (Stage of recovery – extremity turns red)

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 4]]> http://pgblazer.com/?p=14914 2012-05-06T14:41:19Z 2012-05-06T14:41:19Z

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Which scientific principle is the basis for thermodilution method used in measurement of cardiac output?
A. Hagen-poisseuille principle
B. Stewart-hamilton principle
C. Bernoulli’s principle
D. Universal gas equation

Correct answer : B. Stewart-hamilton principle

The volume of blood in the heart and lungs can be measured, by the Stewart-Hamilton principle, as the product of cardiac output and the mean transit time from right atrium to the aortic root.
Ref: http://circ.ahajournals.org/content/33/3/347.abstract

Transpulmonary thermodilution uses the Stewart-Hamilton principle.
Ref: http://en.wikipedia.org/wiki/Cardiac_output

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 3]]> http://pgblazer.com/?p=14911 2012-05-06T10:28:24Z 2012-05-06T10:28:24Z

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Choking is seen in?
a. Revolver
b. Pistol
c. Shotgun
d. Sports rifle

Correct answer : c. Shotgun

In firearms, a choke is a tapered constriction of the gun barrel’s bore at the muzzle end, almost always used with shotguns. The purpose is to decrease the spread of the shot in order to gain better range and accuracy.
Ref: http://en.wikipedia.org/wiki/Choke_(firearms)

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 2]]> http://pgblazer.com/?p=14906 2012-05-06T09:44:12Z 2012-05-06T09:34:14Z

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Bracket calcification is seen in?
a. Meningioma
b. Sturge Weber syndrome
c. Tuberous sclerosis
d. Lipoma of corpus callosum

Correct answer : d. Lipoma of corpus callosum

The bracket sign refers to a radiographic appearance seen with the tubulonodular variety of pericallosal lipoma. It reflects calcification seen at the periphery of the midline lipoma. It is best seen on coronal imaging, and historically was identified on frontal radiographs.
Ref: http://radiopaedia.org/articles/bracket-sign

Tramline calcification is a feature of Sturge-Weber syndrome, and describes the pattern of calcification seen on skull radiology.
www.gpnotebook.co.uk/simplepage.cfm?ID=-1227882448

Sturge weber syndrome: CT scans show the tramline gyriform calcification of apposing gyri that underlies the contrast-enhancing leptomeningeal vascular malformation.

http://emedicine.medscape.com/article/414222-overview#showall

Axial nonenhanced CT image in a patient with tuberous sclerosis reveals subependymal calcifications.
Ref:http://emedicine.medscape.com/article/385549-overview#showall

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pgblazer <![CDATA[AIIMS May 2012 – MCQ 1]]> http://pgblazer.com/?p=14902 2012-05-09T16:13:42Z 2012-05-06T08:55:58Z

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Gallow’s traction is used for ?
a) Fracture shaft of femur
b) Fracture neck of femur
c) Fracture humerus
d) Fracture tibia

(Repeat AIIMS Nov 2010)

Correct answer : a) Fracture shaft of femur

Gallow’s traction is used in infants and children with femoral fractures.

Indications Gallows Traction

  • Child must weigh less than 12 kg
  • Femoral fractures
  • Skin must be intact

Ref: http://www0.sun.ac.za/ortho/webct-ortho/general/trac/trac-2.html

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pgblazer <![CDATA[Conditions causing Charcot’s Joint]]> http://pgblazer.com/?p=14899 2012-05-06T06:14:29Z 2012-05-06T06:14:29Z

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Diseases which result in Charcot’s joint (neuropathic joint) are:

  • Diabetes mellitus
  • Tabes dorsalis
  • Leprosy
  • Amyloidosis
  • Syringomyelia
  • Meningomyelocele
  • Peroneal muscular atrophy

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pgblazer <![CDATA[Causes of exudative pleural effusion]]> http://pgblazer.com/?p=14895 2012-05-05T01:45:43Z 2012-05-05T01:45:43Z

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Causes of exudative pleural effusion are:
  • Neoplasms
  • Pulmonary embolism
  • Infections
  • Collagen vascular disorders
  • GIT disorders – Perforation of esophagus, pancreatitis
  • Others – Yellow nail syndrome, Uremia, Meig’s syndrome, After cardiac surgery / injury, Pericardial disease, Asbestos exposure, Radiation exposure, Chylothorax

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pgblazer <![CDATA[ECG changes in hyperkalemia]]> http://pgblazer.com/?p=14892 2012-05-03T00:59:48Z 2012-05-03T00:59:48Z

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ECG changes in hyperkalemia are:

  • Peaking of T waves
  • Increase in PR interval (AV conduction delay)
  • Wide QRS complex
  • Loss of P waves

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pgblazer <![CDATA[ECG changes in acute pericarditis]]> http://pgblazer.com/?p=14889 2012-05-03T00:52:43Z 2012-05-03T00:52:43Z

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ECG changes in acute pericarditis are:

  • ST elevation with concavity upward
  • T inversion occurs after some days (once ST segment returns to baseline)
  • No change in QRS complexes (decrease in QRS voltage may occur in massive pericardial effusions)
  • PR segment depression (due to atrial involvement)
  • Atrial premature beats, atrial fibrillation

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pgblazer <![CDATA[Causes of high anion gap metabolic acidosis]]> http://pgblazer.com/?p=14886 2012-04-18T16:34:50Z 2012-04-18T16:34:50Z

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The main causes of high anion gap metabolic acidosis are:

  • Lactic acidosis
  • Renal failure
  • Ketoacidosis (alcoholic / starvation / diabetes)
  • Toxin induced (ethylene glycol / methanol / salicylates)

Anion gap is the difference between measured cations and the measured anions – represents the quantity of unmeasured anions in the plasma.

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pgblazer <![CDATA[Branches of external carotid artery]]> http://pgblazer.com/?p=14883 2012-04-17T23:59:35Z 2012-04-17T23:59:35Z

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Branches of external carotid artery are:

  1. Superior thyroid artery
  2. Lingual artery
  3. Facial artery
  4. Occipital artery
  5. Posterior auricular artery
  6. Ascending pharyngeal artery
  7. Maxillary artery
  8. Superficial temporal artery

1,2 and 3 are anterior branches. 4 and 5 are posterior branches. Ascending pharyngeal artery is the only medial branch of external carotid artery. Maxillary artery and superficial temporal artery are the terminal branches.

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pgblazer <![CDATA[Causes of massive splenomegaly]]> http://pgblazer.com/?p=14878 2012-04-14T02:57:37Z 2012-04-13T08:27:30Z

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Some conditions causing massive splenomegaly are:
  • Chronic myeloid leukaemia
  • Chronic lymphocytic leukemia
  • Hairy cell leukemia
  • Myelofibrosis
  • Polycythemia vera
  • Autoimmune hemolytic anemia
  • Sarcoidosis
  • Gaucher’s disease
  • Diffuse splenic hemangiomatosis

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pgblazer <![CDATA[Causes of floppy infant syndrome]]> http://pgblazer.com/?p=14874 2012-04-12T00:36:35Z 2012-04-12T00:36:35Z

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Causes of paralytic FIS:

  • Guillian Barre syndrome
  • Spinal muscular atrophy
  • Myasthenia gravis
  • Myotonic dystrophy
  • Infant botulism

Causes of non paralytic FIS:

  •  Down’s syndrome
  • Cerebral palsy
  • Malnutrition
  • Turner syndrome
  • Marfan syndrome
  • Tay Sachs disease
  • Prader Willi syndrome

(FIS = Floppy Infant Syndrome)

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pgblazer <![CDATA[Risk factors for Acanthamoeba keratitis]]> http://pgblazer.com/?p=14871 2012-04-08T12:37:55Z 2012-04-08T12:37:55Z

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  • Extended wear contact lenses (most important)
  • Use of contact lenses while swimming
  • Use of home made solutions for cleaning contact lenses
  • Washing eyes with contaminated water
  • Airborne contaminants
  • Ocular trauma
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    pgblazer <![CDATA[Medicine – MCQ 173 – Disseminated intravascular coagulation and thrombotic thrombocytopenic purpura]]> http://pgblazer.com/?p=14869 2012-04-05T00:55:08Z 2012-04-05T00:55:08Z

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    Disseminated intravascular coagulation (DIC) differs from thrombotic thrombocytopenic purpura. In this reference the DIC is most likely characterized by:
    A. Significant numbers of schistocytes
    B. A brisk reticulocytosis
    C. Decreased coagulation factor levels
    D. Significant thrombocytopenia

    Correct answer : C. Decreased coagulation factor levels

    In DIC, the levels of coagulation factors are decreased. Whereas in TTP, coagulation factor levels are normal.

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    pgblazer <![CDATA[Complications of meningitis]]> http://pgblazer.com/?p=14866 2012-04-03T01:01:34Z 2012-04-03T01:01:34Z

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  • Hydrocephalus
  • Seizures
  • Cranial nerve involvement
  • Subdural effusion
  • Subdural empyema
  • Cerebral herniation due to increased intracranial tension
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    pgblazer <![CDATA[SPM – MCQ 136 – The usefulness of a screening test]]> http://pgblazer.com/?p=14864 2012-04-01T01:04:43Z 2012-04-01T01:04:43Z

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    The usefulness of a ‘screening test` in a community depends on its :
    A. Sensitivity
    B. Specificity
    C. Reliability
    D. Predictive value

    Correct answer : A. Sensitivity

    A screening test should be sensitive to detect maximum possible cases. Specificity is not as important. After screening, we can apply a confirmatory test with high specificity.

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