The most important adverse effect of thalidomide is teratogenicity. The others include: Peripheral neuropathy Deep vein thrombosis Constipation Rash Fatigue Hypothyroidism Reference: Basic and Clinical Pharmacology, Katzung, 10th
Renal clearance of lithium is decreased by about 25% in those who take diuretics, hence dosage should be adjusted Similar effect is also noted in certain newer NSAID’s
Ten classes of antidiabetic drugs: 1. Biguanides: e.g. Metformin 2. Glinides: e.g. Repaglinide, Nateglinide 3. Sulfonylureas: e.g. Glibenclamide, Glimiperide 4. Alpha-glucosidase inhibitors: Acarbose, Voglibose 5. Thiazolidinediones: e.g. Rosiglitazone,
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