Medical treatment of endometriosis – Gynaecology MCQ

All are true regarding medical treatment of endometriosis except?
A. Oral progestins cause decidualization of endometrial tissue
B. Injectable progestagen is used once in 3 months in the management of pain of endometriosis
C. Levonorgestrel releasing intrauterine system reduces dysmenorrhoea in endometriosis
D. Gestrinone is given orally 2.5 – 5 mg per day to induce endometrial atrophy

Correct answer : D. Gestrinone is given orally 2.5 – 5 mg per day to induce endometrial atrophy

Laparoscopic view of endometriotic lesions in the peritoneum

• Gestrinone has a long half life.
• It is a 19-nortestosterone derivative.
• It is given orally 2.5 to 5 mg twice weekly for 6 to 9 months.
• It has androgenic, antiprogestagenic, antioestrogenic and antigonadotrophic action.

Ref: Textbook of Gynaecology, Sheila Balakrishnan, 1st edition, p150.
Image credits: https://en.wikipedia.org/wiki/File:Peritoneal_endometriosis.jpg