Pathology MCQs Archive
Which of the following is true regarding nuclear fluorescence in systemic lupus erythematosus?
A. Rim staining pattern indicates antibodies to double stranded DNA
B. Homogenous staining reflects antibodies specific to
The gene NPHS1 encodes?
C. Alpha actinin 4
Which of the following is true regarding lymphangioleiomyomatosis?
A. Primarily seen in old age
B. Commonly associated with persistent cough
C. Proliferation occurs in perivascular epithelioid cells
D. Disease is rapidly progressive
The proto oncogene associated with Burkitt lymphoma is?
All are true regarding desmoid tumours except?
A. Consist of large infiltrative masses that do not metastasize
B. Most frequent in old age
C. Mutations occur in the APC gene
Which is a pauci-immune rapidly progressive glomerulonephritis?
A. Lupus nephritis
B. Microscopic polyangiitis
C. IgA nephropathy
D. Goodpasture syndrome
Which of the following is an autosomal recessive disorder?
A. Duchenne muscular dystrophy
B. Friedreich ataxia
C. Wiskott Aldrich syndrome
D. Lesch Nyhan syndrome
The enzyme deficient in Wolman disease is?
A. Alpha galactosidase A
B. Aryl sulphatase A
D. Acid lipase
All of the following diseases are caused by Trinucleotide-Repeat mutations affecting non-coding regions except?
A. Fragile X syndrome
B. Myotonic dystrophy
C. Spinocerebellar ataxia
D. Friedreich ataxia