AIIMS November 2011 – MCQ 1
Drug not used in multiple sclerosis?
A. Interferon 1 alpha
B. Interferon 1 beta
C. Glatiramer acetate
D. Mycophenolate mofetil
Correct answer : D. Mycophenolate mofetil (Mycophenolate mofetil (MMF) is an immunosuppressant and prodrug of mycophenolic acid, used extensively in transplant medicine.)
FDA Approved Disease Modifying Agents used in multiple sclerosis:
Avonex (interferon beta-1a)
Betaseron (interferon beta-1b)
Copaxone (glatiramer acetate)
Extavia (interferon beta-1b)
Gilenya (fingolimod)
Novantrone (mitoxantrone)
Rebif (interferon beta-1a)
Tysabri (natalizumab)
Ref: www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms/treatments/index.aspx
9 Comments
? mycophenolate
Agent used to prevent EDSS in MS? Natalizumab
mycophenolate is answer
About interferon beta1a,
Interferon beta-1a is used to decrease the number of episodes of symptoms and slow the development of disability in patients with relapsing-remitting (symptoms come and go) multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control). Interferon beta-1a has not been shown to help patients with chronic progressive (symptoms are almost always present and worsen over time) MS. Interferon beta-1a is in a class of medications called immunomodulators. It is not known how interferon beta-1a works to treat MS.
and agent used to prevent EDSS ,most established is interferon beta.ref harri which says that other drug are not well trialed.
interferon alfa
mycophenolate…..(answe by exclusion)……rest of the three drugs are mentioned in the treatment of ms…..as per harrison
Que is which one is used
ans is -interferon beta
ans is interfon alpha. mycophenolic acid is used in variant of multiple sclerosis neuromyelitis optica.
no question is not like that…………
q was which drug is used
the question was the drug used and not the drug not used!!!!!!!!!!!!!!!