AIIMS November 2011 – MCQ 23

Which of the following is not associated with a defect in neural migration?
A. Lissencephaly
B. Schizencephaly
C. Polymicrogyria
D. Focal cortical brain maldevelopment

Correct answer : D. Focal cortical brain maldevelopment

The structural abnormalities found in Neuronal Migration Disorderss (NMD) include schizencephaly, porencephaly, lissencephaly, agyria, macrogyria, polymicrogyria, pachygyria, microgyria, micropolygyria, neuronal heterotopias (including band heterotopia), agenesis of the corpus callosum, and agenesis of the cranial nerves.

Ref: National Institute of Neurological Diseases and Stroke – Neuronal Migration Disorders Information Page (www.ninds.nih.gov/disorders/neuronal_migration/neuronal_migration.htm)

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AIIMS November 2011 – MCQ 22

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