AIIMS November 2011 – MCQ 37

If you are working in a primary health center, which anticoagulant should be used to sent a blood sample for estimating glucose?
A. EDTA
B. Heparin
C. NaF + Potassium oxalate
D. Potassium oxalate

(Repeat question – AIIMS Nov 06 – AA q23)

Correct answer : C. NaF + Potassium oxalate

The standard anticoagulant used for glucose estimation is potassium oxalate. But the RBC’s in the sample continue utilising glucose for glycolysis. Thus the glucose level drops 1-2% per hour. In a tertiary care setup, this is not much significant as the sample can reach the lab quickly. But when taking a blood sample in a PHC, there is a delay before reaching the lab. Hence sodium fluoride should be added. It acts as a glycolysis inhibitor.