Amphotericin B toxicity – Pharmacology MCQ

Which of the following is used to decrease the toxicity of amphotericin B?

A. Dose reduction

B. Liposomal delivery systems

C. Supplementing glucose

D. Giving it along with flucytosine

Correct answer : B. Liposomal delivery systems

Liposomal delivery systems decrease the amount of free drug in the blood. Infected cells interact with the liposomes, resulting in the release of amphotericin B at the site of action.

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