Anaesthetic agent in liver and kidney disease – Anaesthesia MCQ
Which anaesthetic agent is preferred in a patient taken for surgery with bilirubin of 8.6 mg/dl and serum creatinine of 2.1 mg/dl ?
A. Atracurium
B. Vecuronium
C. Pancuronium
D. Rocuronium
Correct answer : A. Atracurium
- Atracurium is the preferred muscle relaxant in a patient with liver dysfunction / renal failure
- It undergoes non specific ester hydrolysis and non enzymatic degradation ( Hoffman degradation )
- It does not depend on the liver / kidney for its deactivation
- Other muscle relaxants that can be given in liver / renal disease are Cisatracurium and Mivacurium
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interesting