Biochemistry – MCQ 52 – Factor to be conserved in a protein for its function

There are more than 300 variants of human hemoglobin gene. Among these only a few are fatal. Hence, the most important factor to be conserved in a protein for its function is the:
A. Amino acid sequence
B. Ligand binding residues
C. Structure
D. Environment

Correct answer :B. Ligand binding residues

Ligand binding is most important factor with regard to conservation of protein function.