Biochemistry – MCQ 63 – Base substitution mutation

Base substitution mutations can have the following molecular consequence except:
A. Changes one codon for an amino acid into another codon for that same amino acid
B. Codon for one amino acid is changed into a codon of another amino acid
C. Reading frame changes downstream to the mutant site
D. Codon for one amino acid is changed into a translation termination codon

Correct answer : C. Reading frame changes downstream to the mutant site

Reading frame shift can occur only in case of frame shift mutation – insertion or deletion. Base substitution does not produce reading frame shift.

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