Biochemistry – MCQ 82 – Factors influencing release of Ca2+ from endoplasmic reticulum

Which of the following substances acts to increase the release of Ca2+ from endoplasmic reticulum ?
A. Inositol triphosphate
B. Parathyroid hormone
C. 1,25 dihydroxy cholecalciferol
D. Diacylglycerol

Correct answer : A. Inositol triphosphate

Inositol triphosphate (IP3) and diacylglycerol (DAG) are second messengers for G protein coupled receptors. IP3 stimulates release of calcium from endoplasmic reticulum. DAG activates protein kinase C.

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