Contraindication for thrombolysis – Neurology MCQ

Which of the following is not a contraindication for thrombolysis of acute ischaemic stroke?
A. Blood pressure of 210/110 mm Hg
B. Major surgery 10 days back
C. Ischaemic stroke 2 months back
D. Blood glucose level of 350mg/dl

Correct answer: D. Blood glucose level of 350mg/dl

Contraindications for thrombolysis of acute ischaemic stroke:
1. Intracranial haemorrhage
2. Ischaemic stroke / head trauma in the last 3 months
3. Major surgery in the last 14 days
4. Active bleeding
5. Myocardial infarction in the last 3 months
6. Blood pressure more than 185/110 mm Hg
7. Blood glucose less than 50 mg/dl or more than 400 mg/dl
8. Rapidly improving symptoms
9. Platelet count less than 1,00,000/mm3
10. Use of heparin in the last 48 hours
11. Elevated INR
12. Coma / stupor

Ref: Harrison’s Principles of Internal Medicine, 19th edition, p2562