Paediatrics – MCQ 29 – Beta thalassemia major

All of the following are true of Beta thalassemia major, except:
a) Splenomegaly
b) Target cells on peripheral smear
c) Microcytic hypochromic anemia
d) Increased osmotic fragility

Correct answer : d) Increased osmotic fragility

Osmotic fragility is decreases in Thalassemia. Increased osmotic fragility is seen in hereditary spherocytosis.