Pathology – MCQ 96 – Histologic changes in myocardial infarction

A 60 year old male presented with acute chest pain of 4 hours duration. Electrocardiographic examination revealed new Q wave with ST segment depression. He succumbed to his illness within 24 hours of admission. The heart revealed presence of a transmural haemorrhagic area over the septum and anterior wall of the left ventricle. Light microscopic examination is most likely to reveal:
A. Edema in between normal myofibres
B. Necrotic myofibres with presence of neutrophils
C. Coagulative necrosis of the myocytes with presence of granulation tissue
D. lnliltration by histiocytes with haemosiderin laden macrophages

Correct answer : B. Necrotic myofibres with presence of neutrophils

After 24 hours of myocardial infarction, there is coagulative necrosis of myofibers with neutrophil infiltration.