Pharmacology – MCQ 117 – Biguanides

Which one of the following statements about biguanides is not true?
A. Don’t stimulate insulin Release
B. Decrease hepatic glucose production
C. Renal Dysfunction is not a contraindication for their use
D. Can be combined with sulfonylureas

Correct answer : C. Renal Dysfunction is not a contraindication for their use

Biguanides are contraindicated in renal disease, hepatic disease and conditions causing tissue anoxia due to increased risk of lactic acidosis.

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