Pharmacology – MCQ 24 – All are true about immunosuppressants except?
All are true about immunosuppressants except?
A. Tacrolimus inhibits calcineurin pathway
B. Steroids binds to cytosolic receptors and heat shock proteins
C. Mycophenolate inhibit purine synthesis via GMP dehydrogenase
D. Sirolimus will block kinase in the IL 2 receptor pathway
Correct answer : C. Mycophenolate inhibit purine synthesis via GMP dehydrogenase
Mycophenolate inhibit purine synthesis via IMP (Inosine monophosphate) dehydrogenase