Proto oncogene associated with Burkitt lymphoma – Pathology MCQ

The proto oncogene associated with Burkitt lymphoma is?
A. ABL
B. BRAF
C. HGF
D. MYC

Correct answer : D. MYC

Burkitt lymphoma histopathology – Wright stain

• MYC proto oncogene is associated with Burkitt lymphoma.
• ABL is associated with chronic myelogenous leukemia and acute lymphoblastic leukemia.
• BRAF is associated with melanoma, leukemia and colon carcinoma.
• HGF is associated with hepatocellular carcinoma and thyroid cancer.

Ref: Robbins & Cotran, Pathologic basis of disease, South Asia edition, Vol 1, p284.
Image credits: Ed Uthman, MD. https://en.wikipedia.org/wiki/File:Burkitt_lymphoma,_touch_prep,_Wright_stain.jpg