Site of urea cycle – Biochemistry MCQ

Site of urea cycle is?

A. Liver
B. Kidney
C. GIT
D. Lungs

Correct answer : A. Liver

Site of urea cycle

  • Urea cycle (also known as ornithine cycle / Krebs Henseleit cycle) takes place in the liver
  • It is responsible for the conversion of toxic ammonia (produced by amino acid catabolism) to urea for excretion
  • 5 enzymes are involved in the urea cycle are:
    1. Carbamoyl phosphate synthetase I
    2. Ornithine transcarbamylase
    3. Argininosuccinate synthase
    4. Argininosuccinate lyase (also known as argininosuccinase)
    5. Arginase
  • The first 2 enzymes are located in the mitochondria, whereas the other 3 are located in the cytoplasm
  • The rate limiting enzyme is Carbamoyl phosphate synthetase I

Related Posts