Topical NSAID for ophthalmic use – Ophthalmology MCQ

Which of the following is a topical NSAID for ophthalmic use?

A. Ibuprofen
B. Diflunisal
C. Nepafenac
D. Oxaprozin

Correct answer : C. Nepafenac

Nepafenac is a topically administered NSAID sold as 0.1% eye drops. It is used for the treatment of pain and inflammation in patients undergoing cataract surgery. Nepafenac is a prodrug of amfenac which has COX-1 and COX-2 inhibitor activity. Treatment is started 1 day prior to cataract surgery and is continued 2 weeks postoperatively. Side effects include foreign body sensation and decreased visual acuity.

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