Vitreous humor anatomy

  • Vitreous humor is the transparent, jelly like visual media occupying the posterior 4/5 of eyeball
  • Volume – 4ml
  • Formed of randomly arranged collagen fibers with spheroidal macromolecules of hyaluronic acid in between

Parts of vitreous humor:

  1. Cortical vitreous
    • The outer part of vitreous close to the retina posteriorly and the lens and ciliary body anteriorly
    • Arrangement of collagen fibers is denser
    • These fibrils condense to form a false anatomical membrane
      • anterior hyaloid membrane
        • in front of ora serrata
        • firmly attached to lens in young people and loosely attached in elderly
      • posterior hyaloid membrane
        • behind ora serrata
        • loosely attached to internal limiting membrane of retina at all ages
  2. Body of vitreous (nucleus)
    • The inner zone of vitreous.
    • True biological gel
    • Less dense
    • Liquefactions first start here
    • Cloquet’s canal / hyaloid canal passes through the vitreous from the optic disc to posterior pole of lens
      • It contains the hyaloid artery of the fetus
      • It is of doubtful existence in adults

Attachments of vitreous

  • Vitreous base
    • part  of vitreous which is most firmly attached
    • 4mm area across ora serrata
  • Also attached around optic disc, fovea, posterior surface of lens (Hyaloidocapsular ligament of wieger)

Functions of vitreous

  • Maintains shape of eyeball
  • Maintains intraocular tension
  • Nutritive function
  • As a optically clear media for light to reach the retina