A 30 year old woman presented to the OPD with proximal muscle weakness, ptosis and easy fatigability. Which of following is the most sensitive test to arrive at a diagnosis?
A. Single fiber electromyography
B. Muscle biopsy
C. Measurement of creatinine phosphokinase levels
D. Edrophonium test
Correct answer : A. Single fiber electromyography
Myasthenia gravis – Reversal of ptosis after edrophonium test
- The history and clinical features are suggestive of myasthenia gravis.
- Single fiber electromyography is the most sensitive test for the diagnosis of myasthenia gravis
- Detection of acetylcholine receptor antibodies is the most specific test
- If single fiber electromyography is not given among the options, the next best choice is edrophonium test
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