Pegvisomant is approved for the treatment of? – Pharmacology MCQ
Pegvisomant is approved for the treatment of?
A. Parkinsonism
B. Hyperprolactinemia
C. Amenorrhoea
D. Acromegaly
Correct answer : D. Acromegaly
- Pegvisomant is a polyethylene glycol complexed mutant growth hormone.
- It is used for the treatment of acromegaly caused by small pituitary adenoma.
- It binds to growth hormone receptor and prevents triggering of signal transduction.
- It is a GH antagonist.
Ref: Essentials of Medical Pharmacology, K D Tripathi, 7th ed, p238.