Pegvisomant is approved for the treatment of? – Pharmacology MCQ

Pegvisomant is approved for the treatment of?
A. Parkinsonism
B. Hyperprolactinemia
C. Amenorrhoea
D. Acromegaly

Correct answer : D. Acromegaly

  • Pegvisomant is a polyethylene glycol complexed mutant growth hormone.
  • It is used for the treatment of acromegaly caused by small pituitary adenoma.
  • It binds to growth hormone receptor and prevents triggering of signal transduction.
  • It is a GH antagonist.

Ref: Essentials of Medical Pharmacology, K D Tripathi, 7th ed, p238.