All are true about vitamin D metabolism except?
A. 25 alpha hydroxylation occurs in the liver
B. 1 alpha hydroxylation occurs in the kidney
C. In absence of sun light, the daily requirement is 400- 600 IU per day
D. Williams syndrome is associated with mental retardation, precocious puberty and obesity
Correct answer : D. Williams syndrome is associated with mental retardation, precocious puberty and obesity
Williams syndrome (Williams–Beuren syndrome) is a rare neurodevelopmental disorder characterized by a distinctive, “elfin” facial appearance, along with a low nasal bridge; an unusually cheerful demeanor and ease with strangers; developmental delay coupled with strong language skills; and cardiovascular problems, such as supravalvular aortic stenosis and transient hypercalcaemia.