AIIMS November 2011 – MCQ 78
Mechanism of action of efavirenz is?
A. Inhibition of HIV 1 protease
B. Inhibition of HIV 1 reverse transcriptase
C. Inhibition of HIV 1 integrase
D. Preventing HIV entry into cell
Correct answer : B. Inhibition of HIV 1 reverse transcriptase
Ref: KDT 6th p772
Non nucleoside reverse transcriptase inhibitors (NNRTI’s) – Nevirapine and Efavirenz – These are nucleoside unrelated compounds which directly inhibit HIV reverse transcriptase without the need for intracellular phosphorylation.
3 Comments
option n exam inhibition of reverse trascriptase….
U not mentioned n option…
Ez d right answer…
yes inhibitn of reverse transcriptase was te option instead of nucleosidase
option was transcriptase inhibitor and d right ans,,,,,, no doubt