AIIMS November 2011 – MCQ 88

Collection of Medicine MCQs (Cardiovascular system) for medical students. Concept based MCQs with detailed explanations which help students to gain valuable insights and gain an edge in competitive examinations. More than just answering MCQs, the explanations will improve the knowledge and understanding about the conditions discussed. Also useful for MD students who are preparing for Superspeciality entrance examinations. Medicine MCQs - Cardiovascular System Kindle Edition: Click Here for a Preview. Comments and suggestions are most welcome.

Which of the following is true regarding prothrombin time measurement?
A. Should be measured within 2 hours of obtaining the sample
B. Sample should be refrigerated immediately to preserve coagulant factor function
C. Platelet rich plasma is required
D. Activation is done with kaolin

Correct answer : A. Should be measured within 2 hours of obtaining the sample

The plasma should be assayed withing four hours of blood collection.
Ref: Basic medical laboratory techniques By Barbara H. Estridge, Anna P. Reynolds, Norma J. Walters (via google books)

The specimen for measurement of prothrombin time should not be refrigerated.
Ref: Understanding clinical investigations: a quick reference manual By Susan Skinner (via google books)

Platelet rich plasma is not used of measurement of PT. Instead, tissue factor is used.
Ref: Guyton 11th p467

Kaolin is used for APTT measurement.

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