Anaesthetic agent contraindicated in hypertensives

Anaesthetic agent contraindicated in hypertensives is?

A. Propofol
B. Thiopentone sodium
C. Diazepam
D. Ketamine

Correct answer : D. Ketamine

Anaesthetic agent contraindicated in hypertensives

• Ketamine increases heart rate, cardiac output and blood pressure
• These effects are due to stimulation of the sympathetic nervous system and decrease in reuptake of noradrenaline
• Hence it is contraindicated in:
  • Hypertensives
  • Ischemic  heart disease
  • Congestive cardiac failure
  • Arterial aneurysms
• It is also contraindicated in patients with increased intracranial tension
• It produces dissociative anaesthesia