Causes of renal papillary necrosis

  • Diabetes mellitus – several papillae affected, all of same stage, rarely calcify
  • Analgesic nephropathy – almost all papillae affected, different stage of necrosis,calcification frequent
  • Sickle cell disease – few papillae affected, rarely calcify
  • Obstruction – variable number of papillae affected, calcification frequent

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