Classification of oral hypoglycemic agents

  1. Sulphonyl ureas – first generation (tolbutamide, chlorpropamide); second generation – (glibenglamide, glipizide, gliclazide, glimiperide)
  2. Biguanides – metformin
  3. Meglitinides – repaglinide, nateglinide
  4. Thiazolidine diones – rosiglitazone, pioglitazone
  5. Alpha glucosidase inhibitors – acarbose, miglitol
  6. Dipeptidyl peptidase-4 (DPP-4) inhibitors – sitagliptin
  7. Glucagon like peptide (GLP-1) analogue – exenatide

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Glibenclamide is an oral hypoglycemic drug belonging to the group sulphonyl ureas. It is a second generation sulphonyl urea. Other...