Most common cause of lobar hemorrhage in elderly – Medicine MCQ

Most common cause of lobar hemorrhage in elderly age group ?
A: Hypertension
B: Vascular malformation
C: Coagulopathy
D : Amyloid angiopathy

Correct Answer: D : Amyloid angiopathy

Intraparenchymal bleed with surrounding oedema- CT ScanIntraparenchymal bleed with surrounding oedema- CT Scan

  • Though hypertension is the most common cause of intracerebral hemorrhage, the usual site for it is putamen, thalamus, pons and cerebellum.
  • But lobar hemorrhage in elderly is most commonly due to cerebral amyloid angiopathy, where there is amyloid deposition in the walls of cerebral arteries following arteriolar degeneration.

Ref: Harrison’s principles of internal Medicine, 19 th edition, page 2582 – 2583
Image credits: James Heilman, MD. Licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. https://commons.wikimedia.org/wiki/File:Parachemableedwithedema.png