Most common preceding infection in bone marrow failure syndromes – Medicine MCQ

Which is the most common preceding infection in bone marrow failure syndromes?
A. Parvo B19
B. EBV
C. HIV
D. Hepatitis

Correct Answer : D. Hepatitis

Aplastic anaemia – bone marrow histology

• Most common infection preceding bone marrow failure syndrome is hepatitis.
• It is usually sero negative ( non-A, non- B, non – C ).
• It accounts for 5% of etiologies.
• Parvo virus can cause pure red cell aplasia, but it doesn’t usually cause generalised bone marrow failure.

Ref: Harrison’s principles of internal medicine, 19 th edition, page 664
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