Erlotinib – MCQ

All of the following statement s about ‘Erlotinib’ are true except?
A. Tyrosine kinase inhibitor
B. Food decreases its absorption
C. Rashes may occur
D. Used in non small cell lung carcinoma

Correct answer : B. Food decreases its absorption

  • Oral bioavailability of erlotinib is 60%
  • But when taken along with food, it increases to 100%
  • It should be taken on an empty stomach as there is increased chance of side effects when taken along with food
  • It is used in treatment of non small cell lung cancer and pancreatic cancer
  • Important adverse effects are diarrhoea, acneform rash, fatigue and anorexia

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