Erlotinib – MCQ

All of the following statement s about ‘Erlotinib’ are true except?
A. Tyrosine kinase inhibitor
B. Food decreases its absorption
C. Rashes may occur
D. Used in non small cell lung carcinoma

Correct answer : B. Food decreases its absorption

Oral bioavailability of erlotinib is 60%
But when taken along with food, it increases to 100%
It should be taken on an empty stomach as there is increased chance of side effects when taken along with food
It is used in treatment of non small cell lung cancer and pancreatic cancer
Important adverse effects are diarrhoea, acneform rash, fatigue and anorexia

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