Indications for renal biopsy in nephrotic syndrome

Collection of Medicine MCQs (Cardiovascular system) for medical students. Concept based MCQs with detailed explanations which help students to gain valuable insights and gain an edge in competitive examinations. More than just answering MCQs, the explanations will improve the knowledge and understanding about the conditions discussed. Also useful for MD students who are preparing for Superspeciality entrance examinations. Medicine MCQs - Cardiovascular System Kindle Edition: Click Here for a Preview. Comments and suggestions are most welcome.

The most common variant of nephrotic syndrome in children in Minimal change nephrotic syndrome. In case of MCNS, there is no need to do a renal biopsy before starting treatment. But in certain atypical features at onset, it is necessary to do a renal biopsy. They are:

  • Age of onset less than 12 months
  • Gross hematuria
  • Persistent microscopic hematuria
  • Elevated blood pressure
  • Low blood C3
  • Impaired renal function
  • Proteinuria despite appropriate steroid therapy

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