Inhibitors of oxidative phosphorylation – Biochemistry MCQ

All are inhibitors of oxidative phosphorylation except?
A. Carboxin
B. Oligomycin
C. Valinomycin
D. Atractyloside

Correct answer : A. Carboxin

Mitochondrial electron transport chain

• Carboxin inhibits the transfer of ions from FADH2.
• Oligomycin, Valinomycin and Atractyloside are inhibitors of oxidative phosphorylation.
• Oligomycin inhibits flow of protons through Fo.
• Valinomycin is an ionophore which inhibits oxidative phosphorylation.
• Atractyloside inhibits translocase.

Ref: Textbook of Biochemistry, D. M. Vasudevan & Sreekumari S, 4th edition, page 216.