Kussmaul's sign – Causes, Mechanism

  • Kussmaul’s sign refers to the inspiratory increase in jugular venous pressure (or central venous pressure)
  • Some sources consider Kussmaul’s sign as the absence of inspiratory fall in jugular venous pressure

Causes:

  • Constrictive pericarditis
  • Restrictive cardiomyopathy

Mechanism:

  • Normally there is inspiratory decrease in JVP (Read Mechanism of inspiratory decrease in JVP)
  • In the conditions mentioned above, the pericardium / myocardium is stiff
  • The negative intrathoracic pressure is not transmitted to the heart
  • The heart cannot accommodate the increased blood flow that occurs during inspiration
  • Hence the jugular venous pressure will be elevated