Kveim test

  • Skin test to detect sarcoidosis
  • Intracutaneous injection of spleen extract of patient with sarcoidosis (Kveim antigen)
  • Positive result – granulomas found 4-6 weeks later
  • False negative – corticosteroid therapy
  • Risk of transmission of diseases like bovine spongiform encephalopathy- hence not done nowadays
  • Named after norwegian pathologist Morten Ansgar Kveim

Also called:

  • Nickerson Kveim reaction
  • Kveim Nickerson skin test