Mechanism of resistance in MRSA – MCQ
False regarding Methicillin Resistant Staphylococcus aures (MRSA) ?
A. Resistance may be produced by increased production of beta lactamase enzyme
B. Resistance is primarily plasmid mediated
C. Resistance is due to altered Penicillin Binding Proteins
D. Resistance may be missed at incubation temperature of 37°C during susceptibility testing
Correct answer : B. Resistance is primarily plasmid mediated
Resistance is mediated by the MeC-A gene which codes for altered Penicillin Binding Proteins. MeC-A gene is part of nuclear chromosomes.