Mechanism of resistance in MRSA – MCQ

False regarding Methicillin Resistant Staphylococcus aures (MRSA) ?
A. Resistance may be produced by increased production of beta lactamase enzyme
B. Resistance is primarily plasmid mediated
C. Resistance is due to altered Penicillin Binding Proteins
D. Resistance may be missed at incubation temperature of 37°C during susceptibility testing

Correct answer : B. Resistance is primarily plasmid mediated

Resistance is mediated by the MeC-A gene which codes for altered Penicillin Binding Proteins. MeC-A gene is part of nuclear chromosomes.

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