Medicine – MCQ 106 – Patient with thrombocytosis and structural abnormality of platelets

A patient presents with a platelet count of 700 x 10(9)/L with abnormalitites in size, shape and granularity of platelets. WBC count of 12 x 10(9)/L, hemoglobin of 11g/dl and the absence of Philadelphia chromosome. The most likely diagnosis would be:
a) Polycythemia vera
b) Essential thrombocythemia
c) Chronic myeloid leukemika
d) Leukemoid reaction

Correct answer : b) Essential thrombocythemia