Medicine – MCQ 135 – Features of Mitral valve prolapse

All of the following are true for mitral valve prolapse, except:
A. Transmission may be as an autosomal dominant trait
B. Majority of the cases present with features of mitral regurgitation
C. The valve leaflets characteristically show myxomatous degeneration
D. The disease is one of the common cardiovascular manifestations of Marfan’s Syndrome

Correct answer : B. Majority of the cases present with features of mitral regurgitation

Features of Mitral valve prolapse:

  • Majority of patients are asymptomatic
  • Some present with non specific chest pain, dyspnoea, fatigue or palpitation
  • Myxomatous degeneration of heart valves is seen (mostly mitral valve)
  • Autosomal dominant pattern of inheritance
  • Prominent cardiovascular manifestation of Marfans syndrome
  • Mitral regurgitation can occur as a complication due to rupture of chordae tendinae or failure of papillary muscles