Medicine – MCQ 14 – Least useful investigation in multiple myeloma

The following is the least useful investigation in multiple myeloma:
A. ESR
B. X-Ray
C. Bone scan
D. Bone marrow biopsy

Answer : Bone scan
Osteoblastic activity is suppressed by myeloma cells. (through secretion of cytokines). Hence these site show no increased uptake during bone scan.

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