Medicine – MCQ 144 – Anticentromere antibody

Anticentromere antibodies are most commonly associated with:
A. Diffuse cutaneous systemic sclerosis
B. Mixed connective tissue disease
C. CREST syndrome
D. Polymyositis

Correct answer : C. CREST syndrome

Anticentromere antibodies are seen mostly in those with CREST syndrome. (40-80% patients with CREST syndrome are anticentromere antibody positive)