Medicine – MCQ 99 – Female presenting with anemia and jaundice for 2 years

A 23 year old female presenting with anemia, jaundice, for 2 years, peripheral smear showing spherocytes, the best investigation to be done
a) Reticulocyte count
b) Osmotic fragility test
c) Coombs test
d) Bone marrow aspiration

Correct answer : c) Coombs test