Microbiology – MCQ 67 – Fimbrial adhesion

A microbiologist wants to develop a vaccine for prevention of attachment of diarrhoeagenic E. coli to the specific receptors in the gastro-intestinal tract. All of the following fimbrial adhesions would be appropriate vaccine candidates except :
A. CFA-l
B. P-Pili
C. CS—2
D. K 88

Correct answer : B. P-Pili

P-Pili are involved in the pathogenesis of pyelonephritis. It binds to the P blood group substance on erythrocytes and uroepithelial cells. They have no role in gastrointestinal infection.

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