Microbiology – MCQ 76 – Lab diagnosis of viral infections

Laboratory diagnosis of viral respiratory tract infections can be established by all of the following tests except :
A. Detection of virus specific IgM antibodies in single serum specimen
B. Demonstration of viral antigens by indirect immunofluorescence assay in nasopharyngeal washings
C. Isolation of viruses using centrifugation enchanced culture
D. Detection of viral heamagglutination inhibiting (HAI) antibodies in a single serum specimen

Correct answer : D. Detection of viral heamagglutination inhibiting (HAI) antibodies in a single serum specimen

For diagnosis of viral infection, it is necessary to demonstrate viral heamagglutination inhibiting (HAI) antibodies in at least 2 serum specimens.