Contraindications of Thiopental – Anaesthesia MCQ

Thiopental is contraindicated in all of the following except?
A. Porphyria
B. Status asthmaticus
C. Pericardial tamponade
D. Penetrating eye injury

Correct answer: D. Penetrating eye injury

  • Thiopental is contraindicated in porphyria, status asthmaticus, pericardial tamponade, and severe shock.
  • It causes centrally mediated respiratory depression.
  • It can cause laryngeal spasm and bronchoconstriction in asthmatics.
  • Thiopental causes depression of myocardial contractility.
  • Peripheral vascular resistance falls and it can lead to hypotension, which can be exaggerated if there is hypovolemia.

Ref: Lee’s Synopsis of Anaesthesia. 13th edition. p154, 156.

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