Contraindications of Thiopental – Anaesthesia MCQ

Thiopental is contraindicated in all of the following except?
A. Porphyria
B. Status asthmaticus
C. Pericardial tamponade
D. Penetrating eye injury

Correct answer: D. Penetrating eye injury

Thiopental is contraindicated in porphyria, status asthmaticus, pericardial tamponade, and severe shock.
It causes centrally mediated respiratory depression.
It can cause laryngeal spasm and bronchoconstriction in asthmatics.
Thiopental causes depression of myocardial contractility.
Peripheral vascular resistance falls and it can lead to hypotension, which can be exaggerated if there is hypovolemia.

Ref: Lee’s Synopsis of Anaesthesia. 13th edition. p154, 156.

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